Best Nootropics Guide - The Best Nootropics 2025

ThinkEase's clear and well-dosed ingredient profile is impressive. ThinkEase's formula is a blend of natural ingredients known for cognitive benefits like Citicoline, Rhodiola Rosea, Bacopa monnieri, L-Theanine, Ginkgo biloba, Lion's Mane, and Korean Ginseng.

Citicoline is a naturally occurring compound vital for the synthesis of phosphatidylcholine, a crucial component of cell membranes. Rhodiola Rosea is an adaptogenic herb that enhances cognitive function, reduces mental fatigue, and improves stress resistance. Bacopa monnieri, a traditional Ayurvedic herb, is known for its cognitive-enhancing properties. L-Theanine, an amino acid found primarily in green tea, promotes relaxation, reduces stress, and improves focus and attention. Ginkgo Biloba, a widely used herbal supplement, improves memory, cognitive function, and cerebral blood flow. Lion's Mane, a medicinal mushroom, stimulates nerve growth factor production, improves cognitive function, and protects against neurodegenerative diseases. Korean Ginseng is a well-known adaptogenic herb, it improves cognitive function, reduces mental fatigue, and enhances stress resistance.

Summary

ThinkEase presents a compelling case as a cognitive enhancer, especially for professionals in high-pressure environments, anyone needing help in focusing, or looking to maintain cognitive performance and memory as they age. By enhancing focus and decreasing stress, ThinkEase could contribute to improved productivity, and alleviate feelings of stress or anxiety during high-pressure moments. Its potent blend of natural ingredients, coupled with its scientifically-proven benefits, make it an excellent choice for those seeking to boost their cognitive abilities, whilst also supporting long-term brain health.

One of the main features of NooCube is its entirely natural, non-toxic formula that is free from side effects. The product comprises 13 well-known ingredients in the nootropic world due to their proven effectiveness. Bacopa Monnieri, for instance, is an herb that enhances nerve signal reception, leading to quicker reaction times and improved cognitive functions.

Another ingredient in NooCube is Alpha GPC, which boosts the body's production of acetylcholine, a neurotransmitter essential for memory and learning. Additionally, L-theanine and L-tyrosine are included to improve mood, extend attention span, enhance reaction times, and reduce stress levels and fatigue symptoms.

NooCube also incorporates Huperzine A to bolster memory function and oat straw extract to heighten responsiveness. These ingredients are beneficial for focus and concentration. Resveratrol and pterostilbene, polyphenols commonly found in berries, serve as powerful antioxidants that slow aging and help prevent age-related cognitive decline.

The synergy of these ingredients keeps the brain healthy and fully functional. NooCube enhances cognition and focus, increases energy levels, and combats aging, resulting in a happier, clearer mind and more efficient daily performance. The most recent update to the formula now includes Lutemax 2020, which is scientifically proven to support attention, verbal memory, processing speed, and stress response.

Summary

VyvaMind's ingredient list is quite limited but does include Citicoline. This natural compound provides long-lasting energy levels that can significantly boost your focus and concentration. It's also believed to have significant benefits for long-term brain health.

With only 75mg of caffeine per serving, it's unlikely to leave you feeling jittery or anxious like some other brands. The addition of B vitamins is also helpful memory, mood, and overall brain health.

L-Theanine and L-Tyrosine are also key ingredients in VyvaMind that have numerous benefits, including improved attention span, creativity, and a sense of calm focus.

Summary

VyvaMind is a top-tier nootropic supplement that is affordable and effective. Our testing and review of Vyvamind, found it to be good for anyone looking to elevate their cognitive abilities and achieve their full potential.

Ingredients in ProMind Complex at the time of our review include L-Glutamine, Bacopa Monnieri Extract, Ginkgo Biloba, N-Acetyl L-Carnitine Hydrochloride, Vinpocetine, and Huperzine. Each of these ingredients plays a significant role in how the product works.

L-Glutamine enhances neural communication, reduces anxiety, and maintains brain function by lowering cortisol levels. Bacopa Monnieri Extract is clinically proven to boost memory, support memory retention, and help foster clear thinking. Ginkgo Biloba, combats free radicals, decreases brain damage, and enhances cerebral blood flow.

N-Acetyl L-Carnitine Hydrochloride is vital for a healthy brain, reducing inflammation and optimizing energy production. Vinpocetine increases brain blood flow, facilitates oxygen and glucose uptake, and enhances cerebral metabolism. Lastly, Huperzine serves as a neuroprotective agent, dispelling brain fog, increasing alertness, and fostering clear thinking.

Summary

ProMind Complex is the most effective product we've analyzed and tested as a memory enhancing nootropic. It's effective in boosting cerebral blood flow and slowing neurodegeneration. It also shows significant promise in its ability to guard against degenerative brain diseases like Alzheimer's and in sharpening memory. The supplement is effective in reducing the frequency of 'senior moments' by supporting clear thinking. With ProMind Complex, enhanced memory retention is no longer out of reach.

Our Mind Lab Pro review found that it helps support neural plasticity and combat the natural cognitive decline that comes with aging. Its intelligent blend of 11 natural nootropics includes lion's mane, which promotes optimal NGF production for neural regeneration and maintenance, as well as citicoline, PS, bacopa monnieri, and maritime pine bark, all of which help slow cognitive decline, improve mental clarity, and enhance memory and learning.

The formula also includes both l-tyrosine and l-theanine, which work together to optimize mental performance, reduce the effects of stress and fatigue, and promote greater attention, focus and clarity.

Mind Lab Pro's solid vitamin B complex (including vitamins B6, B9, and B12) works together to improve mental performance, balance your mood, and promote long-term cognitive health, especially against age-related cognitive decline.

Summary

One standout feature of Mind Lab Pro is its inclusion of rhodiola rosea, a well-known herbal adaptogen. Rhodiola rosea helps maintain high levels of cognitive energy, reduces the effects of mental and physical stress, and enhances attention span, mental processing, and work capacity. With rhodiola rosea, Mind Lab Pro delivers clarity while keeping you calm and in a positive mood.

The product's formulation is backed by scientific research, featuring carefully selected ingredients known for their cognitive-enhancing properties. AlphaSize Alpha GPC, Cereboost® American Ginseng Extract, SunPS® Phosphatidylserine, and Huperzine A are among the key ingredients that aim to improve cognitive function, memory, and learning. Other constituents such as L-Tyrosine, Ioniplex® Mineral Complex, Acetyl-L-Carnitine, and L-Phenylalanine are linked to improved cognitive performance, energy metabolism, and overall health. The inclusion of PureWayC® Vitamin C and a B Vitamin Complex further underscores Kaged's commitment to comprehensive health benefits.

In a DBEM study involving athletes, Kaged Mindset exhibited almost immediate impact, a stark contrast to other nootropics that often take days or sometimes weeks to yield perceivable improvements in cognitive performance. The non-caffeinated version provided an initial boost in focus and energy, lasting approximately 1.5 to 2 hours, while the caffeinated version extended these effects to 3-4 hours. It tastes great, is easy to mix and is great on-the-go.

Summary

Kaged Mindset has made a strong entry into the nootropic market. It delivers on its claims of enhanced attention, focus, and productivity while offering a refreshing, easy-to-consume alternative to traditional nootropic capsules. The product's science-backed formulation, coupled with the immediate effects observed in the study, positions it as a promising cognitive-enhancing supplement. While the memory improvement was not immediately evident, it could also yield long-term improvements in this area given the presence of ingredients known to enhance memory function.

The key ingredients include Cognizin® Citicoline, Sharp-PS® Green (Soy-Free) Phosphatidylserine, Ajipure® L-Tyrosine, and Maritime Pine Bark Extract. Citicoline, a versatile nootropic, aids in building and optimizing brain cell functions, raising acetylcholine to support learning, attention, and memory, and stabilizing brain cell membranes for healthy neural repair and function. Phosphatidylserine aids in the efficient function and long-range health of brain cell membranes, while L-Tyrosine and Maritime Pine Bark Extract contribute to brain health and mental clarity.

Summary

Our Performance Lab Mind review found that it stands out as a unique nootropic. It not only enhances cognitive functions but also supports the brain's recovery from mental exertion. Its blend of scientifically-backed ingredients and stim-free formula making it a suitable choice for a wide range of people. With consistent use, Performance Lab Mind is well formulated to support long-term brain health as well as providing more immediate improvements in cognition.

The company's nootropic blends cater to a variety of cognitive functions, including increased cognitive energy, enhanced mental clarity, improved memory and learning abilities, reduced brain fog, elevated mood, and stress reduction. The standout feature is the personalization, which allows users to optimize their cognitive enhancement based on individual needs.

While our Thesis Nootropics review has not conducted independent research on their nootropic blends, they do cite scientific papers in support of several ingredients used. These include Teacrine, Dynamine, Zembrin, Synapsa, Ashwagandha, and Alpha GPC. However, it's important to note that comprehensive evidence is lacking for many of the 30+ ingredients used across their range.

The company offers various blends, each targeting different cognitive aspects. These include the Energy blend (containing choline, NAC, NALT, Sabroxy®, TeaCrine®, Zynamite®, caffeine, and L-theanine), the Clarity blend (7,8-DHF, Alpha GPC, Epicatechin, Lion's Mane, caffeine, and L-theanine), and the Motivation blend (Artichoke extract, Dynamine®, Forskolin, L-phenylalanine, vitamin B12, caffeine, and L-theanine).

Summary

Thesis Nootropics offers a comprehensive, personalized cognitive enhancement solution. The higher price point may deter some, but the tailored approach and expert guidance could justify the additional cost for those seeking an advanced and individualized cognitive enhancement solution. While some ingredients lack comprehensive scientific evidence, the use of recognized nootropic components and personalized guidance may make this a suitable option for those looking to optimize cognitive function.

Our review of Alpha Brain found that it uses proprietary blends, which essentially mask the levels of ingredients used, making it impossible to know which ingredients are clinically dosed and which are there purely for marketing reasons. It's accurate to say that it's not possible for all the ingredients in Alpha Brain to be at clinically proven levels as the amounts of each proprietary blend used is declared.

Alpha Brain's ingredients include l-tyrosine and l-theanine, which help to raise levels of serotonin and dopamine in the body, thus improving cognitive abilities and cutting through brain fog and fatigue. Another important ingredient is oat straw extract, which improves blood flow to the brain and enhances oxygen and glucose delivery to keep the brain sharp and highly energized.

Alpha Brain also focuses on increasing the body's natural production of acetylcholine, an essential neurotransmitter involved in communication within the brain and between the brain and the rest of the body. This is achieved through a combination of Alpha GPC, bacopa, and phosphatidylserine, the latter of which is the only nootropic recognized by the FDA for boosting cognitive function.

Alpha Brain also contains huperzia serrata, which inhibits the production of the catalyst acetylcholinesterase to maintain higher levels of acetylcholine in the body. However, it's worth noting that some of the claims made by Alpha Brain may lack scientific merit, and the other ingredients may not offer any significant cognitive benefits.

Summary

Alpha Brain is a nootropic supplement that aims to improve cognitive function through a unique blend of proprietary supplements and natural ingredients. These supplements work together to optimize serotonin and dopamine response, increase levels of acetylcholine, and aid cellular communication, ultimately resulting in improved mood, energy levels, and faster, more focused thinking.

Some of the claims made by Joe Rogan and Onnit are baseless and some ingredients are proved at dosages too low to be effective. However, it's not a terrible product and some people will experience some cognitive benefits. In our testing, we have found better and cheaper alternatives to Alpha Brain.