Thesis Nootropics Review

Thesis Nootropic Review

February 19, 2024

In this Thesis Nootropics review, we look at a supplement range that promises to boost your brainpower with a lineup of six different blends, each targeting a specific area like energy, focus, or creativity. They say their formulas are tailored just for you, but we're here to take a closer look and see if they really live up to the hype. In this review, we're putting Thesis to the test, diving into what's actually in these supplements and whether the science backs up their big claims. There's a lot of buzz around ingredients like Zynamite® and TeaCrine®, but do they actually work? And with so many options, it's a bit overwhelming—do you really need a separate blend for energy and another for focus?

Plus, we've got some questions about whether these blends might be missing some key ingredients that could make them more effective. We've also compared Thesis with NooCube, arguably the market leading nootropic with its all-in-one approach, claiming to offer a broader range of benefits in a simpler package. Stick with us as we break down the facts and find out if Thesis is the real deal or if you're better off looking elsewhere for your nootropic needs.

Thesis Nootropics Reviews

Overall Verdict

3.3/ 5 Stars

  • Thesis Nootropics are a premium nootropic solution with an innovative level of customization in their product offering.
  • On the whole, the blends are well designed and well dosed.
  • However, the customization approach only draws from a limited range of standardized products. This unnecessarily forces customers to trade-off nootropic benefits, favoring only those deemed most relevant following the completion of a questionnaire.
  • In our view it's unnecessary to prioritize nootropic effects in this way. Instead, we prefer a comprehensive approach, such as that provided by NooCube which balances wide-ranging cognitive and brain health benefits in a single constantly improving formula.
NooCube vs Thesis Nootropics

Introduction To Thesis Nootropics

What sets Thesis Nootropics apart from most nootropic suppliers is their focus on personalization. Instead of offering one-size-fits-all solutions, they provide tailored supplements to cater to individual needs and circumstances through their online platform.

Although the name 'Thesis Nootropics' may sound new, they have been in the market for a while, originally starting as before re-branding. Their extensive experience and more than half a million users attest to their credibility. The vast data they've accumulated from nootropic research is unparalleled, and they use it to refine their formulas with rigorous science and data-driven methods.

The Personalized Nootropic

The personalization process is simple. Customers begin by visiting their website and completing a questionnaire that gathers basic information—no lab tests or medical history required. While some may argue that the approach could be even more detailed, it's a non-invasive method for tailoring recommendations based on individual preferences.

After completing the questionnaire, customers receive their shipment within 1-3 business days. However, Thesis encourages users to treat the initial shipment as a sample, inviting them to test various blends before settling on a specific formula. This feedback helps improve their algorithm and future prescription capabilities.

Though some may view this as a way for the company to encourage additional purchases, it's worth noting that they allow customers to try up to four different blends before committing to a long-term formula. This system helps users refine their choices without the hassle of extensive trial and error.

Personalized Support At A Premium Price

  • Each customer is assigned a personal nootropics expert. This expert serves as a coach and pharmacist, offering virtual consultations to help refine a user's nootropic regimen, track progress, and answer any questions. This elevates Thesis beyond just supplements, making it a comprehensive well-being program.
  • This tailored approach is premium priced. A starter kit is over a hundred dollars, and a monthly prescription costs around eighty dollars. This is more expensive than the highest-quality alternatives like NooCube. Ultimately, consumers must decide whether the additional support and tailoring justify the higher price point.
Thesis Nootropics Reviews

The Nootropic Endorsed by Dr. Andrew Huberman, Rich Roll And Dr. Gabrielle Lyon

  • Dr. Andrew Huberman's claim: "I've been using Thesis for over a year now, and I can confidently say that their nootropics have been a total game changer for me."
  • Rich Roll's claim: "Thesis has provided a substantial benefit to my ability to focus. Creativity works best for me - I take it 30 mins before a podcast or writing and it helps me get in the zone."
  • Dr. Gabrielle Lyon's claim: "I work with CEOs, celebrities, and other top performers in my practice. Thesis is what I recommend and take personally for focus and cognition. I even used it to help me nail my first TedX talk."

Thesis Nootropics Claimed Benefits

Thesis Nootropics Overview

Thesis Nootropics provides a comprehensive cognitive enhancement solution that not only shares the common benefits of other high-quality nootropic supplements but also is a uniquely tailored solution that set them apart from their competitors.

It's important to note that Thesis Nootropics does come at a higher price point compared to alternatives like Hunter Focus. However, the personalized approach and access to expert guidance may justify the additional cost for users who want to invest in a more advanced and tailored cognitive enhancement solution.

What Does Thesis Offer?

Thesis Nootropics offers a variety of blends that cater to multiple aspects of cognitive function. These benefits include increased cognitive energy, enhanced mental clarity, improved memory and learning abilities, reduced brain fog, elevated mood, lowered stress levels, and a boost in focus, among others. These core qualities are what one would expect from a top-tier nootropic supplement, ensuring that users receive the cognitive support they need.

However, Thesis Nootropics goes beyond the standard offerings with two distinct aspects that make it stand out from the crowd. Firstly, the personalization feature allows users to tailor their nootropic experience to their specific needs. While other nootropics like NooCube might work well for most individuals, they may not be 100% optimal for everyone. Personalization can help users target specific cognitive aspects they wish to improve, achieving near-optimal results based on current nootropic research.

This personalization process starts with an easy-to-use online questionnaire that gathers information about the user's preferences and needs. Although some may argue that this approach isn't comprehensive enough for truly personalized supplements, it's a non-invasive method for tailoring recommendations based on individual preferences. This allows users to zero in on their cognitive health and function, addressing areas that need improvement and potentially unlocking that final 5% of cognitive optimization.

The second unique benefit of Thesis Nootropics is access to their team of experts. While this feature may seem unnecessary for those who are content with basic nootropic knowledge, it can be invaluable for users looking to delve deeper into the world of cognitive enhancement. The additional cost for this personalized support can be justified when considering the expert guidance and tailored recommendations provided by the Thesis team.

These experts serve as both coaches and pharmacists, offering virtual consultations to help refine a user's nootropic regimen, track progress, and answer any questions. This level of support elevates Thesis Nootropics beyond just a supplement, turning it into a comprehensive wellbeing program. By working closely with these experts, users can gain a better understanding of their cognitive health and how nootropics can play a role in optimizing their mental performance.

Thesis Nootropics provides a comprehensive cognitive enhancement solution that not only shares the common benefits of other high-quality nootropic supplements but also is a uniquely tailored solution that set them apart from their competitors.

It's important to note that Thesis Nootropics does come at a higher price point compared to alternatives like NooCube. However, the personalized approach and access to expert guidance may justify the additional cost for users who want to invest in a more advanced and tailored cognitive enhancement solution.

Research And Evidence

Thesis haven't conducted independent research into the effectiveness of their nootropic blends. However, they do cite a total of 18 scientific papers in support of 6 of the ingredients used across the range. Whilst this number of citations seems impressive at first, in reality it's 3 citations for each of only 6 ingredients:

  • Teacrine [1,2,3]
  • Dynamine [4,5,6]
  • Zembrin [7,8,9]
  • Synapsa [10,11,12]
  • Ashwagandha [13,14,15]
  • Alpha GPC [16,17,18]

Given that over 30 ingredients are used across Thesis' range, there is a lot of scientific evidence missing. Overall, Thesis nootropics are dosed at effective levels, but some ingredients are not well evidenced - and what evidence is searchable is not easy to locate. 

Ingredients And Options

Nootropic formulations from Thesis encompass various blends, tailored to the individual, concentrating on enhancing distinct aspects of cognitive function and brain health. These blends exhibit unique ingredient compositions, although some similarities are present among them.

The Energy blend, is designed to augment energy levels, combat fatigue, and bolster mental endurance. It incorporates choline, recognized for its benefits in memory and learning, as well as NAC and NALT, which contribute to detoxification and neuronal communication, respectively. Additionally, proprietary ingredients such as Sabroxy® (for dopamine increase and memory enhancement), TeaCrine® (for energy, motivation, and cognitive function), and Zynamite® (for physical and mental energy) are included. Conventional nootropic components, like caffeine (for energy) and L-theanine (for stress response improvement), are also present.

Clarity, has a somewhat unconventional ingredient list, yet still comprises many expected nootropic components. 7,8-DHF and Alpha GPC both facilitate neural communication, neurogenesis, and neuroprotection. Epicatechin and Lion's Mane contribute to neuroprotection while enhancing mood, memory, cerebral blood flow, and memory consolidation. Caffeine and L-theanine are also included, addressing stress response and energy.

The Motivation blend aims to boost willpower and productivity while curbing procrastination, despite motivation being a difficult aspect to define or quantify. Ingredients such as Artichoke extract (for circulation and stress response), Dynamine® (for mood elevation and sustained energy without caffeine-related crashes), Forskolin and L-phenylalanine (together improving cognitive function, mood, and focus), and vitamin B12 (for energy and nerve health) contribute to this goal. Caffeine and theanine are also part of this blend.

The Creativity formula, designed to enhance verbal fluency and confidence, contains Agmatine, Ashwagandha, and L-theanine (for stress and anxiety management), Alpha GPC (for memory, neuroprotection, and neurogenesis), and Zembrin® (for mood regulation and increased cerebral blood flow). Caffeine is also present in this blend.

Lastly, the Confidence blend aims to promote self-assurance by targeting stress and insecurity responses. Ingredients include magnesium, ashwagandha, saffron, sage, and DHH-B, which collectively help improve confidence.

Responsive Table
Blend Name Ingredient Amount
Energy Zynamite® 300mg
Energy TeaCrine® 100mg
Energy Sabroxy® 100mg
Energy CDP Choline 300mg
Energy N-Acetyl-L-Tyrosine 300mg
Energy N-Acetyl Cysteine 500mg
Energy Optional: Caffeine 100mg
Energy Optional: L-Theanine 200mg
Clarity 7,8 Dihydroxyflavone 30mg
Clarity Camellia Sinesis Extract 250mg
Clarity Alpha GPC 250mg
Clarity Epicatechin 250mg
Clarity Lion’s Mane 8:1 Extract 500mg
Clarity Optional: Caffeine 100mg
Clarity Optional: L-Theanine 200mg
Creativity KSM-66 Ashwagandha 300mg
Creativity GS15-4 Panax Ginseng 200mg
Creativity Zembrin® 25mg
Creativity Agmatine Sulfate 250mg
Creativity Alpha GPC 150mg
Creativity Optional: Caffeine 100mg
Creativity Optional: L-Theanine 200mg
Logic Triacetyluridine 30mg
Logic Vegan Omega-3 Lysine complex (EPA + DHA) 200mg
Logic Phosphatidylserine 200mg
Logic Theobromine 100mg
Logic Gingko Biloba 160mg
Logic Synapsa® (Bacopa monnieri extract) 320mg
Logic Optional: Caffeine 100mg
Logic Optional: L-Theanine 200mg
Motivation Forskolin 250mg
Motivation Methylcobalamin 1000mcg
Motivation Dynamine 100mg
Motivation L-Phenylalanine 500mg
Motivation Artichoke Extract 450mg
Motivation Optional: Caffeine 100mg
Motivation Optional: L-Theanine 200mg
Confidence Saffron extract (affron®) 28mg
Confidence Ashwagandha extract (Shoden®) 120mg
Confidence Sage extract 333mg
Confidence Magnesium threonate 50mg
Confidence Magnolia bark extract (DHH-B) 10mg
Confidence Zembrin® 25mg
Confidence Optional: Caffeine 100mg
Confidence Optional: L-Theanine 200mg

Overall: 4.0 / 5

Responsive Table
Test Result
Attention 4.0
Cognition 3.9
Memory 3.8
Mood 4.1
Stress 4.3
Brain Health 4.1
Learning 3.9
Overall 4.0 / 5.0


  • Personalization: Thesis nootropics offer customized blends that cater to individual needs, enhancing the effectiveness of cognitive support.
  • Expert Consultations: Access to expert advice is available, providing valuable guidance and insight for users seeking to optimize their cognitive health.
  • High-Quality Ingredients: Thesis nootropics are formulated with premium ingredients, ensuring safety and effectiveness for consumers.
  • Comprehensive Support: The customer care provided by Thesis not only includes expert consultations, but also extends to answering questions and addressing concerns, contributing to a positive overall experience.


  • Cost: Thesis nootropics may be more expensive than alternatives, potentially deterring budget-conscious consumers.
  • Limited Personalization: Although Thesis offers personalized blends, the customization may not be as precise or in-depth as some consumers would prefer.
  • Subscription Model: Some individuals might find the subscription-based model inconvenient or inflexible, preferring one-time purchases instead.
  • Overemphasis on Customer Care: The extensive customer support, while commendable, may be perceived as excessive by some consumers who prefer a more straightforward, self-directed approach to their supplement regimen.
  • Over complicated approach to nootropics for majority of people. A more comprehensive alternative such as NooCube, is likely to better suit most people's needs.

Potential Side Effects of Thesis Nootropics

  • The Energy blend contains Zynamite®, a natural ingredient derived from the mango tree [19]. It may cause mild side effects, such as headaches, nausea, and stomach discomfort. TeaCrine® and Sabroxy® are also included in this blend, which may cause nervousness, insomnia, and jitteriness. Caffeine and L-Theanine, which are optional ingredients, may also cause similar side effects.
  • The Clarity blend contains 7,8 Dihydroxyflavone, a natural ingredient that may cause mild side effects, such as nausea, diarrhea, and headaches [20]. Camellia Sinesis Extract, which is also included, may cause insomnia, nervousness, and stomach discomfort. Lion’s Mane 8:1 Extract may cause itching, skin rashes, and gastrointestinal discomfort [21].
  • The Creativity blend contains KSM-66 Ashwagandha, which may cause mild side effects, such as stomach discomfort and diarrhea [22]. GS15-4 Panax Ginseng may cause nervousness, insomnia, and headaches. Zembrin® may cause dizziness, nausea, and dry mouth [23].
  • The Logic blend contains Triacetyluridine, which may cause mild side effects, such as headaches, nausea, and stomach discomfort [24]. Vegan Omega-3 Lysine complex (EPA + DHA) may cause gastrointestinal discomfort and nausea. Theobromine may cause insomnia, restlessness, and stomach discomfort [25].
  • The Motivation blend contains Forskolin, which may cause stomach discomfort, diarrhea, and headaches [26]. Methylcobalamin may cause mild side effects, such as nausea and diarrhea. Dynamine may cause nervousness, insomnia, and headaches [27].
  • The Confidence blend contains Saffron extract (affron®), which may cause mild side effects, such as dry mouth, dizziness, and nausea [28]. Ashwagandha extract (Shoden®) may cause stomach discomfort, diarrhea, and headaches [29]. Sage extract may cause gastrointestinal discomfort, nausea, and headaches.

Best Alternative to Thesis Nootropics

If your focus is sharply honed on enhancing a particular aspect of cognitive function and you don't mind shelling out more for targeted support, Thesis might suit your needs. Its range of blends is designed to pinpoint specific nootropic benefits, whether that's boosting your energy, improving clarity, sparking creativity, enhancing logic, motivating success, or building confidence. But, it comes at a premium, both in terms of cost and the necessity to navigate through its segmented approach to find what works best for you.

However, for those seeking a broader spectrum of cognitive benefits—encompassing not just temporary performance boosts but also long-term brain health, mood stabilization, and memory enhancement—there are more comprehensive and cost-effective alternatives available. Among these, NooCube stands out in our testing as the most effective nootropic available. NooCube's formula supports overall brain function without the need to mix and match different products. It delivers a synergistic blend of ingredients known for their efficacy in enhancing cognitive function, supporting neuron health, and providing the body with the foundational nutrients necessary for optimal mental performance. With NooCube, we experienced a more holistic approach to cognitive enhancement, making it our top recommendation for those looking to invest in their brain health and cognitive capabilities.

Thesis Nootropics vs NooCube


4.9 / 5

While Thesis aims to focus on specific areas of brain health with different products, NooCube makes things simpler. It's one supplement that aims to boost memory, help you focus better, and make your mind clearer. NooCube packs ingredients like Panax Ginseng, L-Theanine, and Bacopa Monnieri, each and every ingredient is proven to support cognition and brain health in clinical studies - and each has been dosed at clinically proven levels.

Thesis' approach is interesting but the cost, complexity and narrow range of benefits let it down. If you're looking for something that covers more bases and keeps everything straightforward, NooCube is the way to go. With its latest update in February 2024, NooCube has gotten even better, making it a top choice for anyone looking to give their brain a comprehensive boost.


The element of personalization offered by Thesis, albeit imperfect, adds a unique approach to the market. However, it's questionnable whether there's a real need for this. A comprehensive solution such as NooCube serves as a reliable alternative, as it encompasses the benefits of multiple blends provided by Thesis. NooCube has continued to evolve, and its latest formulation released in February 2024, takes the industry leading supplement to even greater heights.

From a financial standpoint, it is important to evaluate the costs associated with the product and the accompanying customer support. Although the quality of Thesis' customer support is commendable, their relevance to a broader audience may be limited. For those who perceive value in the additional support, the investment may be warranted. However, for many consumers, the costs may be excessive.

To put it into perspective, purchasing a month's supply of Thesis nootropics without a subscription equates to approximately 3 months of NooCube. This alternative offers a top-quality nootropic at a more reasonable price point - and without having to invest time into completing a questionnaire.


Do nootropics work?

Many nootropic ingredients and formulations have been shown to improve attention, memory, and learning, while others may promote relaxation and reduce stress and anxiety. For example, caffeine is a commonly used nootropic that can increase alertness and reduce fatigue, while L-Theanine, an amino acid found in tea leaves, has been shown to promote relaxation and reduce stress.

Are nootropics safe?

Nootropics that contain natural ingredients and have undergone clinical testing are generally considered safe when used properly. It is important to follow recommended dosages and to avoid taking more than the recommended amount. It's also worth being aware of any potential side effects and if necessary consult with your doctor if you have any underlying medical conditions.

What should I expect from a nootropic?

When taking a nootropic supplement, you should expect to experience some improvement in cognitive function, such as enhanced memory, concentration, and mental clarity. The effects of a nootropic will vary depending on the specific ingredients and dosage of the supplement, as well as individual factors such as age, overall health, and your lifestyle.

Which nootropic should I buy?

Popular nootropic supplements include NooCube, Mind Lab Pro, and Vyvamind. NooCube contains a blend of ingredients that may improve memory, focus, and overall cognitive function. Mind Lab Pro is designed to support brain health and cognitive performance through a variety of ingredients, including vitamins, minerals, and plant-based compounds. Vyvamind is a premium nootropic supplement that focuses almost exlcusively on cognitive function and mental performance. Read DBEM's guide to nootropics to see how the leading nootropic brands compare.


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  19. Zynamite®:
  20. 7,8 Dihydroxyflavone:
  21. Lion’s Mane 8:1 Extract:
  22. KSM-66 Ashwagandha:
  23. Zembrin®:
  24. Triacetyluridine:
  25. Theobromine:
  26. Forskolin:
  27. Dynamine:
  28. Saffron extract (affron®):
  29. Ashwagandha extract (Shoden®):