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Neuriva vs Prevagen - Our Firsthand Testing And Results

Neuriva vs Prevagen Review

November 5, 2024

Over the past 18 months, through November 2024, we’ve tested Neuriva vs Prevagen to see how they stack up for boosting memory, focus and overall brain health. We've tested both firsthand and analyzed the science behind every ingredient they each include in their formulation. If you’re keen to understand which one might work best for you, this review will break down the pros and cons of each. Many people are looking for ways to support their mental clarity and focus, and these two supplements have become popular choices. So, which one should you pick? Or are there other options worth considering?

Overall Verdict


 Neuriva & Prevagen


  • Neuriva's limited ingredient profile, featuring Coffee Fruit Extract and Phosphatidylserine, lacks comprehensive scientific backing for overall cognitive enhancement.
  • Prevagen, while claiming to improve memory, has been found guilty of questionable marketing practices and making misleading claims about the product's efficacy.
  • Our firsthand experience with Neuriva and Prevagen resulted in only limited cognitive improvements. This is likely due to their basic ingredient profiles.
  • Our Recommendation. Unlike Neuriva and Prevagen, NooCube delivers on its promises and then some. Featuring a scientifically validated formula, including key ingredients like Bacopa Monnieri and L-Theanine, NooCube worked to improve focus, mitigated anxiety and helped us sustain energy levels. Its ingredients promote cognitive function and long-term brain health. For a comparable price point, NooCube offers more comprehensive benefits, giving you more bang for your buck.
Neuriva vs Prevagen Test Results

Introduction - Neuriva vs Prevagen

Over the last 18 months, up to November 2024, we’ve tested Neuriva and Prevagen to see what they actually do for memory and focus. Neuriva uses Coffee Fruit Extract and Phosphatidylserine to help brain cells communicate better, while Prevagen includes Vitamin D and a unique ingredient called Apoaequorin, which is supposed to support memory.

Both products sound promising, but we’re here to give you an honest look. We’ll cover the ingredients, what the research says, and our own experience with each. Plus, we’ll see if there might be other options out there that could work even better.

This guide breaks down the facts about Neuriva and Prevagen so you can decide what’s best for you, without the marketing fluff.

What are Nootropics?

Nootropics, often dubbed "smart drugs" or "cognitive enhancers," are substances formulated to amplify mental performance. The term itself was coined by Dr. Corneliu Giurgea in 1972, who set criteria for these substances, such as enhanced learning and memory, increased efficacy under disruptive conditions, and the absence of typical pharmacological effects like sedation[1].

Originally, nootropics were developed to treat cognitive decline in older adults and enhance cognition in people with neurodegenerative diseases. Fast-forward a few decades, and nootropics have gone mainstream. They're not just for scientists or Silicon Valley entrepreneurs anymore. From college students to multitasking parents, a broad swath of people is exploring these substances to get an "edge" on their cognitive functions.

But let's not get ahead of ourselves. While the promise of smarter thinking and razor-sharp focus sounds fantastic, it's essential to weigh in on the risks. On the one hand, some nootropics have shown promising results in terms of memory enhancement, focus, and even mood stabilization[2]. But it's crucial to note that the effects can vary based on individual physiology and the specific compounds used. On the flip side, there's the question of long-term safety. Not all nootropics have undergone rigorous scientific scrutiny, and potential side effects—though often mild—can include headaches, sleep disruption, and gastrointestinal distress[3].

So, as we delve into the specific merits and demerits of Neuriva and Prevagen later on, it's good to keep this bigger picture in mind. Nootropics are no magic bullets, but under the right circumstances, they could offer some intriguing benefits for your brain.

Neuriva: An Overview

Neuriva comes from the labs of Schiff Vitamins, a stalwart in the health and wellness arena with a track record spanning over eight decades[4]. Schiff's portfolio is broad and diverse, encapsulating not only cognitive enhancers like Neuriva but also a gamut of other vitamins, minerals, and supplements tailored for myriad health concerns.

The company is recognized for its commitment to quality and ethical practices. They follow stringent manufacturing guidelines and are transparent about their sourcing procedures, ensuring consumer trust. Schiff Vitamins has carved out a notable presence in the market, courtesy of its years of experience and diverse product range[5].

However, the effervescence around Neuriva isn't solely about the Schiff brand. It also encircles the efficacy—or potential lack thereof—of its chosen ingredients, Coffee Fruit Extract and Phosphatidylserine. While the brand comes with a legacy of trust, questions have been raised regarding the empirical substantiation of Neuriva's ingredients and their actual impact on cognitive functions[6].

As we compare Neuriva vs. Prevagen, bear in mind this multi-faceted picture of Neuriva—a product with a solid company backing, but one that also invites scientific scrutiny for its ingredient profile.

Prevagen vs Neuriva

Neuriva Ingredient Profile

Neuriva Ingredients (click to reveal)

  • Coffee Fruit Extract (100mg)
  • Phosphatidylserine (100mg)

When it comes to Neuriva, the formulation hinges primarily on two active ingredients: Coffee Fruit Extract (100mg) and Phosphatidylserine (100mg). Let's dissect what science has to say about them.

Coffee Fruit Extract (100mg)

This extract comes from the fruit that encases the coffee bean. Although often discarded during the coffee production process, emerging research suggests potential cognitive benefits. Specifically, some studies show that it may increase the levels of brain-derived neurotrophic factor (BDNF), a protein crucial for brain health[7].

Phosphatidylserine (100mg)

Phosphatidylserine is a fatty substance found in the brain and is involved in the clotting function and maintenance of cellular function in the brain. Clinical trials have offered evidence that phosphatidylserine might aid memory and cognition, especially in older adults[8].

Scientific Backing

While both ingredients appear promising, it's vital to understand that the evidence is still not robust enough to make definitive claims. For example, phosphatidylserine does have some supporting data for cognitive enhancement, but mostly in older populations. Coffee fruit extract, on the other hand, is a relative newcomer in the scientific discourse around nootropics[9].

Side Effects

As for adverse effects, both ingredients are generally considered safe. Phosphatidylserine may cause mild stomach upset and insomnia in some individuals. Coffee fruit extract has a better safety profile but should be consumed cautiously by those sensitive to caffeine or other stimulants.

So, what's the bottom line? Neuriva's ingredient profile appears intriguing but warrants further scientific validation. The product has low-risk side effects but whether it delivers a real cognitive punch is still a subject of ongoing research.

Neuriva Ingredients Label

Neuriva Claims

The claims made by the manufacturer for Neuriva are indeed all-encompassing. From "helping you focus in" to "reacting with greater speed and precision," the product promises a range of cognitive enhancements. Notably, the claims also extend to memory retention, specifying that Neuriva will "help you record and recall stored information" and "retain new information." Further, the product asserts that it will assist users in maintaining prolonged concentration on tasks[10].

Who is Neuriva For?

According to the manufacturer, these cognitive boosts are universal, suggesting that Neuriva could be beneficial for virtually anyone looking to get a mental edge. However, it's worth pointing out that much of Neuriva's marketing is skewed towards older consumers looking for a mental boost to combat cognitive decline.

Critical Examination

While these claims certainly make Neuriva sound like a panacea for cognitive function, the scientific foundation to support these sweeping claims is not entirely bulletproof. For instance, studies on Phosphatidylserine indicate potential benefits for older adults but do not universally validate the extensive claims made by Neuriva[11]. Similarly, coffee fruit extract has shown promise in increasing BDNF levels, but this doesn't directly translate to enhanced focus or memory[12].

Neuriva's broad claims should be interpreted with a level of caution. As with any supplement, individual results may vary, and scientific backing for these specific claims remains to be unequivocally substantiated.

Firsthand Experience with Neuriva

After testing Neuriva consistently over an 18-month period through November 2024, we found that whilst there were some minor positive effects, they were subtle, falling short of the strong promises made in the product’s advertising.

What We Experienced

When we started taking Neuriva, we were optimistic, as the claims about improved focus and memory are appealing. Over the months, we did notice some small shifts in our mental clarity. There was a very slight lift in focus, and the sense of mental fog seemed to lessen a tiny bit. But these changes were not as dramatic as we’d hoped. It was a mild boost rather than a significant improvement[13].

For example, if we previously had trouble concentrating on tasks for extended periods, there was a bit more steadiness in focus, but it wasn’t a game-changing effect. The “helping to focus in” effect that the product mentions did seem to be there, but only slightly. So, while there was some benefit, it didn’t feel like a major change or a fully reliable solution for focus or memory challenges.

Mild Effects

The effects we noticed were modest. The coffee fruit extract, one of the main ingredients, is known for giving a quick mental boost because it contains compounds that stimulate the brain. We anticipated feeling at least a temporary sense of heightened mental clarity, but the results were less obvious than expected[14]. Similarly, the phosphatidylserine in Neuriva, which has been studied for its potential to help with memory, especially in older individuals, didn’t seem to produce strong effects over time. Although there was some improvement, it didn’t fully match up to the high claims made by Neuriva’s makers[15].

Ingredient Takeaways

When looking closer at the ingredient list, it becomes a bit clearer why our results were mild. Both coffee fruit extract and phosphatidylserine have some supportive research backing them, but generally, they are known to produce moderate effects rather than major changes. The dosages in Neuriva aren’t very high either, which could explain why we only noticed small shifts in focus and memory. Based on the product’s composition, it seems more likely to produce gradual effects that may benefit some users over time but not offer a powerful, immediate boost.

Neuriva might provide some people with a slight enhancement in focus and memory, but it doesn’t seem to deliver the bigger results the advertising suggests. For those looking for a gentle cognitive boost, it may offer some help, but it’s unlikely to create dramatic changes in mental clarity or memory retention.

Prevagen: An Overview

Manufacturer & Company Background

Prevagen is produced by Quincy Bioscience, a biotech firm hailing from Madison, Wisconsin. This company is known for manufacturing brain- supplements, but with some controversy[16].

Ethical Practices

In 2017, the Federal Trade Commission (FTC) and the state of New York called Quincy Bioscience into question for allegedly making false claims about Prevagen's cognitive benefits. This legal kerfuffle came to a head in 2020 with a court-mandated settlement[17].

Market Presence

Prevagen's popularity has not waned substantially despite these setbacks. However, consumers should be aware that the product's touted efficacy now comes with a court-approved disclaimer. This reads that the cognitive benefits are "based on a clinical study of subgroups of individuals who were cognitively normal or mildly impaired"[18].

Critics argue that the caveat's wording may be too technical for the average Joe or Jane, potentially leading them to pull the trigger on a purchase without fully grasping what they're getting into[19].

When weighing Prevagen as an option, it's crucial to note both its market traction and the questions around its claims. A scientific lens should be applied when considering this product, given its controversial background and the legally required disclaimers.

Neuriva vs Prevagen Review

Prevagen Ingredient Profile

Prevagen Ingredients (click to reveal)

  • Vitamin D (50mcg)
  • Apoaequorin (10mg)

Key Ingredients

Prevagen primarily boasts two key ingredients in its formula: Vitamin D (50mcg) and Apoaequorin (10mg).

Scientific Backing

The science behind Apoaequorin, originally derived from jellyfish, remains a subject of debate. The primary claim is that it assists in calcium regulation within brain cells, potentially benefiting cognitive function[20]. However, comprehensive scientific validation of these claims is not robustly established. As for Vitamin D, its role in brain health is more universally accepted, but it's generally not seen as a potent cognitive enhancer on its own[21].

Side Effects

In terms of adverse effects, Prevagen appears to be generally safe for consumption, but it's crucial to note that individual responses can vary. Some people report mild gastrointestinal distress or headaches, though these are not definitively linked to the product[22].

In summary, while the Apoaequorin in Prevagen might sound like the latest and greatest, it's important to exercise critical thinking. The ingredient profile is limited, and the scientific backing, particularly for Apoaequorin, is not entirely ironclad. Given this, a careful weigh-in of potential benefits versus unproven effectiveness is advised.

Prevagen Ingredients Label

Prevagen Claims

Claims by the Manufacturer

The creators of Prevagen pitch it as an over-the-counter panacea for bolstering brain function and ameliorating memory. Specifically, they assert that "Prevagen has been clinically shown to safely and effectively improve memory." These statements, they claim, are substantiated by a clinical study involving subgroups of individuals categorized as cognitively normal or only mildly impaired[23].

Who is Prevagen For?

Who is this supplement designed for? The marketing material suggests that Prevagen is intended for adults, particularly those who may be experiencing mild cognitive impairment or concerns about memory loss. It seems to target those who are looking for an over-the-counter remedy without the red tape of prescriptions and medical consultations.

Critical Examination

It's important to underline that the scientific rigor behind Prevagen's claims has been disputed. In fact, the Federal Trade Commission and the state of New York took legal action against the manufacturers for making unsubstantiated claims, leading to 

If you're considering Prevagen for its nootropic effects, it would be prudent to approach these claims with a pinch of skepticism. The supplement might be appropriate for individuals wanting to experiment with cognitive enhancers but remember, the current scientific landscape doesn't wholly endorse the grandiose claims made by the product.

Firsthand Experience With Prevagen

Over an 18-month test period ending in November 2024, we tried Prevagen to see if it lives up to its promises. We followed the recommended daily dose carefully to get a clear sense of its effects on memory and focus.

What We Noticed

The results were mild. After a year and a half, the only consistent effect was a small boost in focus, and even that was subtle and could have been influenced by other daily factors. Improvements in memory were barely noticeable, and we didn’t see any big changes in overall mental sharpness.

Ingredients and Limitations

Prevagen contains just two main ingredients: Vitamin D and Apoaequorin. Apoaequorin, a protein derived from jellyfish, has been studied for memory support, but research results are mixed, so there’s no solid evidence it can reliably improve cognitive function[24]. Vitamin D is essential for general health, but its direct impact on memory is uncertain[25].

The amounts of these ingredients are also on the low side, with 10mg of Apoaequorin and 50mcg of Vitamin D. Compared to other brain supplements that include a variety of well-studied ingredients, Prevagen’s simple formula may explain why we only saw mild effects.

Summary of Our Experience

From our experience, Prevagen offers only minor benefits, mostly a slight improvement in focus. If you’re looking for a more noticeable boost in memory or mental clarity, you might find better options with other supplements that use a broader mix of proven ingredients.

Neuriva vs Prevagen: Side-by-Side Comparison

When choosing the right nootropic for your needs, several factors come into play, such as manufacturer reputation, ingredient profile, efficacy, safety, and cost. Neuriva and Prevagen differ considerably - our table provides an at-a-glance summary of these two products and our personal experiences with each of them.

CATEGORY

NEURIVA

PRevagen

Manufacturer

Schiff Vitamins

Quincy Bioscience

Key Ingredients

Coffee Fruit Extract (100mg)

Phosphatidylserine (100mg)

Vitamin D (50mcg)

Apoaequorin (10mg)

Claims

Focus enhancement, information retention, increased concentration

Improved memory and healthy brain function

Efficacy (Our Experiences)

Moderate; subjective experiences suggest mild cognitive improvements.

Limited; claims have been subject to legal scrutiny. Personal trials show minimal impact.

Safety

Generally safe; no major side effects noted in most individuals.

Mostly safe; some reports of minor digestive discomfort.

Cost

Varies, but generally mid-range in cost for nootropics.

Higher end of the market, especially given its limited ingredient profile.

Overall

Some limited but perceivable effects, but there are better options available such as NooCube.

Limited effects and questionable evidence for claims made by the manufacturer.

Efficacy: Neuriva vs Prevagen

When it comes to the efficacy of Neuriva and Prevagen, it's essential to parse through both scientific literature and real-world experiences. Let's unpack this, shall we?

Scientific Studies:

  1. Neuriva: The active ingredients in Neuriva are Coffee Fruit Extract and Phosphatidylserine. Research indicates that Phosphatidylserine may support cognitive function, including memory and concentration[26]. However, the Coffee Fruit Extract's cognitive effects are less substantiated in peer-reviewed studies.
  2. Prevagen: This product's main unique component is Apoaequorin, a protein originally found in jellyfish. While the company cites a clinical study supporting its efficacy, the scientific community largely considers the evidence as inconclusive[27]. Additionally, the brand faced legal scrutiny over these claims[28].

Firsthand Experience:

  1. Neuriva: Our trial revealed only modest improvements in focus and memory retention. These subjective experiences align reasonably well with the limited yet promising scientific data on Phosphatidylserine.
  2. Prevagen: We noticed minimal to no effect on cognitive function during our test period. This limited impact is unsurprising given the ongoing debate regarding Apoaequorin’s efficacy and the legal scrutiny the company has faced.

So, what's the verdict? If you're looking for a supplement backed by more rigorous scientific studies, Neuriva has a slight edge, mainly due to its inclusion of Phosphatidylserine. However, neither supplement dramatically transformed our cognitive functions during the test periods.

It's worth noting that individual experiences can vary. Therefore, while neither product seems to be a silver bullet for cognitive enhancement, Neuriva appears to offer a somewhat more grounded approach based on existing scientific evidence.

Safety: Neuriva vs Prevagen

When venturing into the realm of nootropics, it's not just efficacy that's crucial; safety is equally paramount. Here's a peek into the safety profiles of Neuriva and Prevagen.

Side Effects:

  1. Neuriva: Generally, Neuriva is considered to be safe and well-tolerated. Its key ingredient, Phosphatidylserine, is generally recognized as safe (GRAS) by the FDA[29]. There might be some mild gastrointestinal discomfort, but this is rare and generally not severe.
  2. Prevagen: Side effects are minimal, but because Apoaequorin is relatively new to the market, long-term data is lacking[30]. Some users have reported headaches, but these cases are isolated.

Warnings, Recalls, and Legal Rulings:

  1. Neuriva: As of now, there are no official warnings or recalls for Neuriva. The ingredient profile is considered relatively innocuous.
  2. Prevagen: In contrast, Prevagen has faced legal scrutiny. The Federal Trade Commission (FTC) and the State of New York filed complaints against the company for making unproven claims[31]. The matter settled in 2020 with a court-approved disclaimer stating that its efficacy is based on a study of a specific subgroup of individuals[32].

While neither product has severe known side effects, Prevagen's legal baggage might be a point of concern for some. The lack of long-term data for Apoaequorin adds another layer of uncertainty.

In summary, both Neuriva and Prevagen have relatively mild side-effect profiles. However, Neuriva gains a slight upper hand in the safety category, being backed by an ingredient that has received GRAS status from the FDA. As always, consult with a healthcare provider before beginning any new supplement regimen.

Cost: Neuriva vs Prevagen

When evaluating nootropics, it's not just about what might rev up your neural engines; your wallet has a stake in this game too. Let's delve into the economic aspects of Neuriva and Prevagen.

Price per Dose:

  1. Neuriva: Priced at $32.99 for a 30-day supply, Neuriva comes to $1.10 per daily dose. This is relatively affordable for the average consumer interested in cognitive enhancement.
  2. Prevagen: Slightly more expensive, Prevagen retails for $39.95 for a month's supply, translating to $1.33 per day. The marginal cost difference could add up over extended periods[33].

Discounts and Subscriptions:

  1. Neuriva: Neuriva operates a point-based loyalty program where you earn 10 points for every dollar spent (330 points for a single product purchase). However, these points mainly provide access to sales events and minor loyalty rewards, which may not necessarily translate into significant savings.
  2. Prevagen: Prevagen offers 15% discounts quite frequently. The consistent discount offering makes Prevagen slightly more budget-friendly in the long term, especially for dedicated users[34].

While the base price per dose gives Neuriva a modest edge, the frequent discounts offered by Prevagen level the playing field. Both products offer value but in different ways: Neuriva with a lower initial investment and Prevagen with potential long-term savings.

When considering which nootropic to go for, weigh your options between the initial cost and the potential long-term benefits offered through loyalty programs or frequent discounts. And as always, measure these economic factors against the efficacy and safety of each product for a more holistic decision-making process[35].

Customer Reviews: Neuriva vs Prevagen

Ah, the all-important voice of the people—customer reviews can be both illuminating and murky waters to wade through. For Neuriva and Prevagen, the overall sentiment is decidedly mixed. A significant number of customers report lower-than-expected efficacy for both products[36]. In the sphere of cognitive enhancement, where individual variability can significantly impact outcomes, this isn't entirely surprising.

As for the trustworthiness of these reviews, tread cautiously. Data from both companies—reviews and scientific claims alike—should be digested with a grain of salt. This caveat is particularly relevant for Prevagen, manufactured by Quincy Bioscience. The company has a history of legal issues regarding their marketing practices, making it advisable to treat their information with additional scrutiny[37]. Given that, unbiased, third-party reviews or peer-reviewed studies should be your go-to resources for an even-handed picture of these products.

Remember, the plural of 'anecdote' is not 'data.' Customer reviews provide individual experiences that are helpful but should not replace comprehensive scientific research. Always consult reliable sources and perhaps even healthcare providers when deciding the right nootropic for your needs. Make sure to weigh these factors in conjunction with efficacy, safety, and cost to make a well-rounded decision[38].

Best Alternative to Neuriva and Prevagen

Whilst it's worth noting it's a capsule product, rather than a powder blend, NooCube stands out as a superior way to increase focus whilst reducing anxiety, alongside a wide range of additional cognitive benefits.

NooCube vs Vyvamind

NooCube


4.9 / 5


NooCube is our leading choice after more than 18 months of reviewing numerous nootropics. We've observed consistently positive results with NooCube across various mental areas, including improved memory, sharper focus, reduced stress, and a noticeable boost in overall mental performance. For those seeking a reliable, effective supplement, NooCube offers strong value and effectiveness.

In contrast to the simpler formulations of Neuriva and Prevagen, which provide limited support, NooCube includes a blend of well-researched ingredients with solid scientific backing. Ingredients like Bacopa Monnieri, L-Theanine and LuteMax 2020 make NooCube a more complete approach to supporting brain function and mental clarity.

Conclusion

In this Neuriva vs Prevagen review, we evaluated what each product claims to do, how well it performs, its ingredients, cost and feedback from users. While both Neuriva and Prevagen have their positives, neither showed consistent results that met the high expectations of noticeable cognitive improvement.

Neuriva is made with Coffee Fruit Extract and Phosphatidylserine, two ingredients that have some support for mental benefits. Prevagen includes Vitamin D and Apoaequorin, a protein that’s thought to help with memory. However, the research on these ingredients isn't very strong and our own experience reflected that. Although each supplement showed mild effects, they weren’t enough to deliver a solid mental boost. Both products are in a similar price range, with some discounts and loyalty rewards offered here and there.

For those looking for something more effective, NooCube has proven to be a better option for us. NooCube combines ingredients with more substantial research supporting their benefits for memory, focus and mental clarity. With NooCube, you get a well-rounded formula that targets several aspects of cognitive function.

Throughout our testing, NooCube consistently provided noticeable improvements in mental clarity and focus without any side effects. It quickly became our preferred supplement for cognitive support, offering reliable results that felt much closer to the claims on the label. The formulation in NooCube, combined with a reasonable price, makes it a good choice if you’re looking for a brain supplement that supports cognitive performance and brain health.

FAQs

Do nootropics work?

Many nootropic ingredients and formulations have been shown to improve attention, memory, and learning, while others may promote relaxation and reduce stress and anxiety. For example, caffeine is a commonly used nootropic that can increase alertness and reduce fatigue, while L-Theanine, an amino acid found in tea leaves, has been shown to promote relaxation and reduce stress.

Are nootropics safe?

Nootropics that contain natural ingredients and have undergone clinical testing are generally considered safe when used properly. It is important to follow recommended dosages and to avoid taking more than the recommended amount. It's also worth being aware of any potential side effects and if necessary consult with your doctor if you have any underlying medical conditions.

What should I expect from a nootropic?

When taking a nootropic supplement, you should expect to experience some improvement in cognitive function, such as enhanced memory, concentration, and mental clarity. The effects of a nootropic will vary depending on the specific ingredients and dosage of the supplement, as well as individual factors such as age, overall health, and your lifestyle.

Which nootropic should I buy?

Popular nootropic supplements include NooCube, Mind Lab Pro, and Vyvamind. NooCube contains a blend of ingredients that may improve memory, focus, and overall cognitive function. Mind Lab Pro is designed to support brain health and cognitive performance through a variety of ingredients, including vitamins, minerals, and plant-based compounds. Vyvamind is a premium nootropic supplement that focuses almost exlcusively on cognitive function and mental performance. Read DBEM's guide to nootropics to see how the leading nootropic brands compare.

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